Rejuran at nüseoul: A Complete Introduction & FAQ

nüseoul
Jan 30
4 min read

Rejuran is one of the most talked-about Korean skin treatment brands — and for good reason. Known for its powerful regenerative properties, Rejuran works at a cellular level to repair damaged skin, improve texture, and restore long-term skin health rather than offering a temporary glow.

At nüseoul, we offer a curated range that includes Rejuran i, Rejuran Healer, and Rejuran HB+, each designed for different skin concerns and areas. Below, we answer the most frequently asked questions to help you understand which option may be right for you.

What is Rejuran?

Rejuran is a Korean brand that makes the most popular and talked about treatments made from polynucleotides (PN) — DNA fragments derived from salmon. These polynucleotides are biocompatible with human skin and are clinically proven to stimulate skin repair, collagen production, and cellular regeneration.

Rather than filling or freezing the skin, Rejuran improves skin quality from within, making it a cult-favourite for those seeking natural, healthy-looking skin.

What Rejuran products does nüseoul carry?

From February 2025, we will offer three of the most popular and used products from the Rejuran line:

Rejuran i – for the delicate eye area
Rejuran Healer – for overall skin regeneration and repair
Rejuran HB+ – for hydration, glow, and improved comfort during treatment

Treatment	Best For	Key Benefits	Texture/Feel	Ideal Areas	Downtime	Pain / Comfort
Rejuran i	Delicate eye area	Strengthens thin under-eye skin, softens fine lines, improves crepiness	Lighter, eye-specific PN	Under-eyes, crow’s feet	2-3 days	Mild–moderate
Rejuran Healer	Overall skin repair & regeneration	Improves skin quality, elasticity, pores, acne-damaged skin, fine lines	Thicker PN formula	Face	3-5 days	Moderate–high (no anaesthetic)
Rejuran HB+	Hydration + regeneration with comfort	Deep hydration, glow, improved texture, more comfortable treatment	Thinner PN formula	Face, neck, hands	2-3 days	Low-mild (~53% less pain vs Healer)

Rejuran i FAQs

What is Rejuran i?

Rejuran i is specifically formulated for the eye area, where the skin is thinner and more delicate.

What concerns does it target?

Fine lines under the eyes
Crepey or thin skin
Dark circles caused by skin quality
Early signs of ageing around the eyes

How is it different from tear trough filler?

Rejuran i does not add volume like filler. Instead, it strengthens and regenerates the skin itself, making it ideal for patients who want subtle, natural improvement without changing their eye shape.

How is Rejuran i administered?

Rejuran i is injected using micro-injections placed superficially into the skin around the eye area. By using the bleb technique, where small, evenly spaced micro-deposits are placed into the skin, these temporary blebs allow the polynucleotides to distribute gradually and stimulate regeneration from within.

What amount is used for Rejuran i?

1cc per treatment. This is specifically formulated for the eye area and is sufficient to treat both under-eyes.

Rejuran Healer FAQs

What is Rejuran Healer best for?

Rejuran Healer is ideal for improving:

Skin texture and elasticity
Fine lines and early signs of ageing
Acne-damaged or compromised skin
Enlarged pores and dullness

It’s often described as a “skin healer” because it focuses on long-term repair rather than instant results.

Which areas can be treated?

Common areas include:

Face

How is Rejuran Healer administered?

Rejuran Healer is delivered via multiple micro-injections across the treatment area, targeting the skin’s dermal layer where collagen and repair processes occur.

What needle technique is used?

The bleb technique is used, creating small raised bumps that settle naturally within 48-72 hours. This method ensures even coverage and optimal skin regeneration.

What amounts are available for Rejuran Healer?

2cc – half face
4cc – whole face

Rejuran HB+ FAQs

What does HB+ mean?

HB+ combines polynucleotides (PN) with hyaluronic acid (HA) and lidocaine.

What are the benefits of Rejuran HB+?

Deep hydration and glow

Improved skin texture

Faster recovery compared to Rejuran Healer
More comfortable treatment experience due to lidocaine

This is a great option if you want regenerative benefits with added hydration and a slightly more “glowy” finish.

What needle technique is used?

We again use the bleb technique, allowing for even distribution, improved hydration, and a smoother recovery.

What amounts are available for Rejuran HB+?

2cc – half face
3cc – whole face
4cc – whole face and neck

This flexibility allows treatments to be tailored depending on the areas that you want to target plus tailor the concentration.

Pain & Comfort: Rejuran Healer vs Rejuran HB+

Discomfort is one of the most common concerns with Rejuran treatments, particularly due to the thickness of polynucleotides and the micro-injection (bleb) technique used. At nüseoul, comfort is a key consideration when selecting the most suitable formulation for your skin and pain tolerance.

Rejuran Healer

Does not contain an anaesthetic
Sensation is often described as sharp or stinging, particularly in thinner skin areas
Discomfort is short-lived but can feel intense during injection
Well tolerated by most patients, especially with topical numbing and experienced technique

Rejuran HB+

Contains lidocaine, a local anaesthetic
Clinically shown to reduce procedural pain by approximately 53% compared to original Rejuran Healer
Generally described as significantly more comfortable, with less stinging during injection
Ideal for patients who are pain-sensitive or new to Rejuran treatments

Which Rejuran Is Right for Me?

Rejuran i is best suited for the delicate eye area, targeting fine lines, thinning, and crepey under-eye skin—without adding volume or altering eye shape.
Rejuran Healer is ideal if your priority is deep, long-term skin repair and improved texture across the face. For those seeking maximum regenerative results and comfortable with brief procedural discomfort, it remains the gold standard.
Rejuran HB+ is a great option if you’re looking for hydration, glow, and skin regeneration with a more comfortable treatment experience. Its added lidocaine makes it especially suitable for patients who prioritise comfort without compromising results.

Many patients benefit from combining treatments—for example, Rejuran Healer for the face and Rejuran i for the eye area—to achieve balanced, natural results.

Still not sure which Rejuran is right for you?

Every skin is different, and the best results come from choosing the right formulation, technique, and treatment plan for your skin. At nüseoul, our doctors take a personalised, skin-first approach to assess your concerns and recommend whether Rejuran i, Rejuran Healer, Rejuran HB+, or a combination is most suitable for you.